Nick started the Hands Off Our Hospital campaign in 2004 in response to the then Labour Government's plans to downgrade Chase Farm Hospital. Nick opposed the BEH Clinical Strategy which recommended replacing 24-hour A&E with an Urgent Care Centre and consultant-led maternity with a midwife-led unit.

On becoming an MP Nick continued to campaign against changes at Chase Farm. In March 2011 he led a cross-party delegation to meet Health Secretary Andrew Lansley, the result of which saw Enfield Council given the opportunity to produce a plan to rival the BEH Clinical Strategy and save services at Chase Farm.

The Independent Reconfiguration Panel (IRP) ruled that the council's plan "does not provide any credible alternative to the current proposals" and therefore backed the BEH Clinical Strategy. Health Secretary Andrew Lansley endorsed their decision, leading Nick to criticise both the IRP and the Health Secretary, saying "I'm disappointed by the IRP's decision. Frankly I think it's the wrong decision. Chase Farm Hospital should have a 24-hour A&E unit, end of story. I also think the Secretary of State is wrong to endorse the IRP's decision".

When Enfield Council proposed seeking a judicial review of the Health Secretary's decision, Nick gave the Labour administration his full support. So did local Conservative councillors. The subsequent decision by Enfield Council not to challenge the decision in court led the Enfield Advertiser to accuse Labour of "cowardice", saying the people of Enfield have been "failed by their council".

Nick still maintains that Chase Farm should have a 24-hour A&E unit and consultant-led maternity services.